Study Finds Agentic Pipelines Improve Clinical Grounding in ICU Mortality Explanations

Summary

A revised feasibility study compares a standalone LLM with a four-step agentic pipeline for explaining ICU mortality predictions. The agentic approach avoided explicit outcome leakage and improved guideline grounding, value specificity, and plausibility, while the standalone model showed stronger SHAP alignment and direction consistency. The authors recommend attribution-based checks before high-stakes clinical use.